This special issue describes state-of-the-art statistical research in adaptive and sequential methods and the application of such methods in clinical trials. It provides 1 review article and 5 research articles contributed by some of the leading experts in this field. The review article gives a comprehensive overview of the outstanding methodology in the current literature that is related to adaptive and sequential clinical trials, while each of the 5 research articles addresses specific critical issues in contemporary clinical trials, as summarized below.
Zhao, Y., Chen, Z., Huang, X., & Tighiouart, M. (2013). Adaptive and Sequential Methods for Clinical Trials. Journal of Probability and Statistics, Article ID 386058, 1-2. doi: 10.1155/2013/386058
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.