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Publications from 2015

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Stochastic Optical Reconstruction Microscopy Imaging of Microtubule Arrays in Intact Arabidopsis thaliana Seedling Roots, Bin Dong, Xiaochen Yang, Shaobin Zhu, Diane C. Bassham, and Ning Fang

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Crystallographic and Spectroscopic Snapshots Reveal a Dehydrogenase in Action, Lu Huo, Ian Davis, Fange Liu, Babak Andi, Shingo Esaki, Hiroaki Iwaki, Yoshie Hasegawa, Allen M. Orville, and Aimin Liu

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May the Best Molecule Win: Competition ESI Mass Spectrometry, Sarah R. Laughlin and W. David Wilson

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Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library, Lei Li, Yunpeng Liu, Cheng Ma, Jingyao Qu, Angie D. Calderon, Baolin Wu, Na Wei, Xuan Wang, Yuxi Guo, Zhongying Xiao, Jing Song, Go Sugiarto, Yanhong Li, Hai Yu, Xi Chen, and Peng George Wang

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Understanding mixed sequence DNA recognition by novel designed compounds: the kinetic and thermodynamic behavior of azabenzimidazole diamidines, Ananya Paul, W. David Wilson, David Boykin, and Yun Chai

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O-GlcNAcylation of G6PD Promotes the Pentose Phosphate Pathway and Tumor Growth, Xiongjian Rao, Xiaotao Duan, Weimin Mao, Xuexia Li, Zhonghua Li, Qian Li, Zhiguo Zheng, Haimiao Xu, Min Chen, Peng George Wang, Yingjie Wang, Binghui Shen, and Wen Yi

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Benz[c,d]indolium-containing Monomethine Cyanine Dyes: Synthesis and Photophysical Properties, Eduardo Soriano, Cory Holder, Andrew R. Levitz, and Maged Henary

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Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys, John K. Thuita, Kristina K. Wolf, Grace A. Murilla, Arlene S. Bridges, David Boykin, James N. Mutuku, Qiang Liu, Susan K. Jones, Charles O. Gem, Shelley Ching, Richard R. Tidwell, Michael Z. Wang, Mary F. Paine, and Reto Brun

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Pancreas-Targeted NIR Fluorophores for Dual-Channel Image-Guided Abdominal Surgery, Hideyuki Wada, Hoon Hyun, Christina Vargas, Julien Gravier, GwangLi Park, Sylvain Gioux, John V. Frangioni, Maged Henary, and Hak Soo Choi

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Integrative Modeling of Macromolecular Assemblies from Low to Near-Atomic Resolution, Xiaojun Xu, Chunli Yan, Robert Wohlhueter, and Ivaylo Ivanov

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Hydrogen Sulfide Prodrugs—A review, Yueqin Zheng, Xingyue Ji, Kaili Ji, and Binghe Wang

Publications from 2014

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Simultaneous Mapping of Pan and Sentinel Lymph Nodes for Real-Time Image-Guided Surgery, Yoshitomo Ashitate, Hoon Hyun, Soon Hee Kim, Jeong Heon Lee, Maged Henary, John V. Frangioni, and Hak Soo Choi

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Design and Synthesis of Heterocyclic Cations for Specific DNA Recognition: From AT-Rich to Mixed-Base-Pair DNA Sequences, Yun Chai, Ananya Paul, Michael Rettig, W. David Wilson, and David Boykin

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Myoplasmic resting Ca2+ regulation by ryanodine receptors is under the control of a novel Ca2+-binding region of the receptor, Yanyi Chen, Shenghui Xue, Juan Zou, Jose Lopez, Jenny J. Yang, and Claudio Perez

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Glycan based detection and drug susceptibility of influenza virus, Hieu Dinh, Xiaohu Zhang, Joyce Sweeney, Yang Yang, Yun He, Abasaheb Dhawane, and Suri S. Iyer

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Spectrophotometric and Spectrofluorimetric Studies on Azilsartan Medoxomil and Chlorthalidone to Be Utilized in Their Determination in Pharmaceuticals, Walid M. Ebeid, Ehab F. Elkady, Asmaa A. El-Zaher, Ramzia I. El-Bagary, and Gabor Patonay

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Prostate Cancer Metastatic to Bone has Higher Expression of the Calcium-Sensing Receptor (CaSR) than Primary Prostate Cancer, Jie Feng, Xiaojun Xu, Bo Li, Edward Brown, Alton B. Farris, Shi-Yong Sun, and Jenny J. Yang

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Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides, Zhen Huang, Rob Abdur, Oksana Gerlits, Jianhua Gan, Jozef Salon, Andrey Y. Kovalevsky, Alexander A. Chumanevich, and Irene Weber

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DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents, Kevin J. Koeller, G Davis Harris, Karl Aston, Gaofei He, Carlos H. Castaneda, Melissa A. Thornton, Terri G. Edwards, Shuo Wang, Rupesh Nanjunda, W. David Wilson, Chris Fisher, and James K. Bashkin

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A Novel Approach Using Electrospray Ionization Mass Spectrometry to Study Competitive Binding of Small Molecules with Mixed DNA Sequences, Sarah R. Laughlin, Siming Wang, Arvind Kumar, David Boykin, and W. David Wilson

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Iron(II)-Catalyzed Intermolecular Amino-Oxygenation of Olefins through the N−O Bond Cleavage of Functionalized Hydroxylamines, Deng-Fu Lu, Cheng-Liang Zhu, Zhen-Xin Jia, and Hao Xu

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Nonproteolytic Roles of 19S ATPases in Transcription of CIITApIV Genes, Nagini Maganti, Tomika Moody, Agnieszka D. Truax, Meghna Thakkar, Alexander M. Spring, Markus W. Germann, and Susanna F. Greer

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The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine, Manoj Munde, Arvind Kumar, Paul Peixoto, Sabine Depauw, Mohamed A. Ismail, Abdelbasset A. Farahat, Ananya Paul, Martial V. Say, Marie-Hélène David-Cordonnier, David Boykin, and W. David Wilson

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The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine, Manoj Munde, Arvind Kumar, Paul Peixoto, Sabine Depauw, Mohamed A. Ismail, Abdelbasset A. Farahat, Ananya Paul, Martial V. Say, Marie-Hélène David-Cordonnier, David Boykin, and W. David Wilson

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Prototype Nerve-Specific Near-Infrared Fluorophores, Min Ho Park, Hoon Hyun, Yoshitomo Ashitate, Hideyuki Wada, GwangLi Park, Jeong Heon Lee, Costyl Njiojob, Maged Henary, John V. Frangioni, and Hak Soo Choi

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Mechanistic Heterogeneity in Site Recognition by the Structurally Homologous DNA-Binding Domains of the ETS-Family Transcription Factors Ets-1 and PU.1, Shuo Wang, Miles H. Linde, Manoj Munde, Victor W. Carvalho, W. David Wilson, and Gregory M. K. Poon

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Kinetics and Structures on the Molecular Path to the Quadruplex Form of the Human Telomere, W. David Wilson and Ananya Paul

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Identification of an L-Phenylalanine Binding Site Enhancing The Cooperative Responses of The Calcium Sensing Receptor to Calcium, Chen Zhang, Yun Huang, Yusheng Jiang, Nagaraju Mulpuri, Ling Wei, Donald Hamelberg, Edward M. Brown, and Jenny J. Yang

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Role of Ca2+ and L-Phe in Regulating Functional Cooperativity of Disease- Associated ‘‘Toggle’’ Calcium-Sensing Receptor Mutations, Chen Zhang, Nagaraju Mulpuri, Fadil M. Hannan, M. Andrew Nesbit, Rajesh V. Thakker, Donald Hamelberg, Edward M. Brown, and Jenny J. Yang

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Direct Determination of Multiple Ligand Interactions with the Extracellular Domain of the Calcium Sensing Receptor, Chen Zhang, You Zhuo, Heather A. Moniz, Shuo Wang, Kelley W. Moremen, James H. Prestegard, Edward M. Brown, and Jenny J. Yang

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Structures of Darunavir-Resistant HIV‑1 Protease Mutant Reveal Atypical Binding of Darunavir to Wide Open Flaps, Ying Zhang, Yu-Chung E. Chang, John M. Louis, Yuan Fang Wang, Robert W. Harrison, and Irene Weber

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Effect of Ca2+ on the Steady-State and Time-Resolved Emission Properties of the Genetically Encoded Fluorescent Sensor CatchER, You Zhou, Kyril M. Solntsev, Florence Reddish, Shen Tang, and Jenny J. Yang

Publications from 2013

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Extracellular Calcium Modulates Actions of Orthosteric and Allosteric Ligands on Metabotropic Glutamate Receptor 1alpha, Jason Y. Jiang, Mulpuri Nagaraju, Rebecca C. Meyer, Li Zhang, Donald Hamelberg, Randy A. Hall, Edward M. Brown, P. Jeffrey Conn, and Jenny J. Yang

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Conformational Plasticity of an Enzyme during Catalysis: Intricate Coupling between Cyclophilin A Dynamics and Substrate Turnover, Lauren C. McGowan and Donald Hamelberg

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Structure-dependent Inhibition of the ETS-Family Transcription Factor PU.1 by Novel Heterocyclic Diamidines, Manoj Munde, Shuo Wang, Arvind Kumar, Chad E. Stephens, Abdelbasset A. Farahat, David Boykin, W. David Wilson, and Gregory M. K. Poon

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Structural Insights of Non-canonical U*U Pair and Hoogsteen Interaction Probed with Se Atom, Jia Sheng, Jianhua Gan, Alexei S. Soares, Jozef Salon, and Zhen Huang

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2-Selenouridine Triphosphate Synthesis and Se-RNA Transcription, Huiyan Sun, Sibo Jiang, Julianne Caton-Williams, Hehua Liu, and Zhen Huang

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Opening Pathways of the DNA Clamps Proliferating Cell Nuclear Antigen and Rad9-Rad1-Hus1, Xiaojun Xu, Carlo Guardiani, Chunli Yan, and Ivaylo Nikolaev Ivanov

Publications from 2012

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Simultaneous Determination of Sitagliptin and Metformin in Pharmaceutical Preparations by Capillary Zone Electrophoresis and its Application to Human Plasma Analysis, Mohamed Salim, Nahed El-Enany, Fathalah Belal, Mohomad Walash, and Gabor Patonay

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Di-cationic arylimidamides Act Against Neospora caninum tachyzoites by Interference in Membrane Structure and Nucleolar Integrity and are Active Against Challenge Infection in Mice, Michelle Schorer, Karim Debache, Fabienne Barna, Thierry Monney, David Boykin, Chad E. Stevens, and Andrew Hemphill

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Insight into the Modulation of Shaw2 Kv Channels by General Anesthetics: Structural and Functional Studies of S4-S5 linker and S6 C-terminal peptides in micelles by NMR, Jin Zhang, Xiaoguang Qu, Manuel Covarrubias, and Markus W. Germann

Publications from 2011

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The Effect of Varying Short-Chain Alkyl Substitution on the Molar Absorptivity and Quantum Yield of Cyanine Dyes, Gala Chapman, Maged Henary, and Gabor Patonay

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HER2 Targeted Molecular MR Imaging Using a De Novo Designed Protein Contrast Agent, Jingjuan Qiao, Shunyi Li, Lixia Wei, Jie Jiang, Robert Long, Hui Mao, Ling Wei, Liya Wang, Hua Yang, Hans E. Grossniklaus, Zhi-Ren Liu, and Jenny J. Yang

Publications from 2006

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Ventrolateral Prefrontal Cortex Activation and Attentional Bias in Response to Angry Faces in Adolescents with Generalized Anxiety Disorder, Christopher Monk, Eric E. Nelson, Erin B. McClure, Karin Mogg, Brendan P. Bradley, Ellen Leibenluft, James R. Blair, Geng Chen, Dennis S. Charney, Monique Ernst, and Daniel S. Pine

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Limbic Hyperactivation During Processing of Neutral Facial Expressions in Children with Bipolar Disorder, Brendan A. Rich, Deborah T. Vinton, Roxann Roberson-Nay, Rebecca E. Hommer, Lisa H. Berghorst, Erin B. McClure, Stephen J. Fromm, Daniel S. Pine, and Ellen Leibenluft

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EcoScale, a Semi-quantitative Tool to Select an Organic Preparation Based on Economical and Ecological Parameters, Koen Van Aken, Lucjan Strekowski, and Luc Patiny

Publications from 2003

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Prevention of Poxvirus Infection by Tetrapyrroles, Avril RM Chen-Collins, Dabney W. Dixon, Andrei N. Vzorov, Luigi G. Marzilli, and Richard W. Compans