Date of Award
Master of Science (MS)
Dr. Keith Pascoe - Chair
Dr. Alfons Baumstark - Co-Chair
Dr. Jerry Smith
Dr. Davon Kennedy
The purpose is to isolate a natural compound, which shows a high activity against Candida albicans, from plant, Vincetoxicum stocksii. Bio-Assay, Thin layer Chromatography, Column Chromatography, TLC bio Assay, and other extraction techniques are used in order to isolate the active compound. First, bio assay technique is carried out on the crude gum. Next, several flash chromatography columns are carried out in order to isolate the target compound, which has a Rf value of ~0.53 in 10:1 DCM/methanol solvent mixture. The TLC bioassay technique is also carried out in order to confirm the hypothesis that the target compound is indeed active.
Momin, Vasim Rasul, "The Analysis of Antimicrobial Testing Vincetoxicum stocksii and Isolation of a Highly Active Compound Against Candida albicans by Using Various Different Techniques.." Thesis, Georgia State University, 2008.