Preliminary experimental results on synthetic datasets generated with various sequencing parameters and distribution assumptions show that TRIP has increased transcriptome reconstruction accuracy compared to previous methods that ignore fragment length distribution information.
Mangul et al.: TRIP: a method for novel transcript reconstruction from paired-end RNA-seq reads. BMC Bioinformatics 2012 13(Suppl 18):A11. doi: 10.1186/1471-2105-13-S18-A11
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