South Asian Americans, one of the fastest-growing subgroups of Asian Americans, face distinct mental health challenges due to complex cultural processes such as acculturation, enculturation, and bicultural identity integration (BII) (Siddiqui, 2022; SAALT, 2019). Despite higher prevalence rates of mental health conditions like depression and anxiety, South Asian Americans underutilize professional mental health services, often relying on informal support systems due to cultural stigma, religious beliefs, and familial expectations (Inman et al., 2014; Garland et al., 2005; Shahid, 2021). This dissertation examined the role of cultural adaption processes in professional mental health help-seeking among South Asian Americans. Chapter 1 systematically reviewed the literature on acculturation, enculturation, and help-seeking in this population and found that acculturation was generally associated with more favorable attitudes towards mental health help-seeking, whereas enculturation was more often associated with less favorable attitudes towards seeking psychological help. Building from this literature, Chapter 2 tested whether BII, acculturation, and enculturation were associated with help-seeking attitudes, intentions, and behavior, and whether gender moderated these associations. These models were tested in a sample of South Asian American adults using multiple, hierarchical, and logistic regression in SPSS; moderation analyses were conducted using SPSS PROCESS Macro (Hayes, 2013). Contrary to the stated hypothesis, results indicated that enculturation was positively associated with help-seeking attitudes and intentions, whereas bicultural identity integration and acculturation were not significant predictors. Bicultural identity integration also did not account for additional variance beyond acculturation and enculturation. The main effects model predicting help-seeking behavior was not significant. However, gender moderated the association between enculturation and help-seeking behavior, such that higher enculturation was associated with lower odds of professional mental health help-seeking among women. This finding highlights the complexity of cultural adaption processes in South Asian American help seeking. Critical implications from the findings and future directions are further discussed.