The Adult Consumers of Tobacco Study 2 (ACTS2) dataset contains data from all participants who completed at least part of the baseline survey from September 2022-July 2023. Participants included U.S. adults 18 years or older who were recent initiators or current established users of then market-leading brands of e-cigarettes at the time of screening [initiated Logic (Power, Pro), NJOY (Ace, Daily), or Vuse (Solo, Vibe, Ciro) within the past 6 months or currently use Juul, Puff (Bar, Plus, Flow, Max), or Vuse Alto]. Those who screened as eligible and fully completed the baseline survey were invited to complete 11 monthly surveys and one final 12-month survey.