Discrimination has been noted as an important acculturative stressor for international students. Multiple studies also showed that different forms of perceived discrimination were related to worse mental health for international students. However, the existing reviews on discrimination did not specify the unique type of discrimination international students might experience, such as language discrimination, and xenophobia, nor did they explore the unique moderators in the acculturation process. Therefore, I conducted a meta-analysis to evaluate the relationship between perceived discrimination and psychological well-being for international students, synthesized current research findings, and tested the potential between-study moderators in a systematic way. Across 58 studies, a negative and medium-to-strong relationship between perceived discrimination and psychological well-being emerged, showing that students with higher levels of perceived discrimination experienced worse psychological well-being. Further, perceived discrimination was more strongly related to negative psychological well-being indicators (e.g., depression, anxiety; r = -0.35), compared to positive psychological well-being indicators (e.g., life satisfaction, self-esteem; r = -0.27). Lastly, the review revealed the underrepresentation of South Asian international students in the current literature, and the need to incorporate and examine important contextual factors for international students. Social belonging is one important factor that might be protective for students experiencing discrimination. However, there were mixed findings related to whether social connections with others and a sense of belonging serve as protective factors for international students experiencing perceived discrimination, and under what circumstances. The second part of the project aims to understand the mental health effects of perceived discrimination for Asian international students and the moderation effects of financial stress and campus belonging, under the unique social and cultural context during COVID-19. The results indicated a 3-way interaction between cultural discrimination, campus belonging, and financial stress in their relationship with psychological distress, showing that the protective effect of campus belonging to buffer against cultural discrimination is contingent upon individuals’ perceived financial stress. The impact of racial discrimination on distress appears invariant, regardless of one’s social or financial resources. These results underscore the importance of taking into consideration the financial and social factors when developing interventions or providing services to support international students dealing with discrimination.