The study of cannabis, also commonly known as marijuana, presents an intriguing topic of research, as its significance extends beyond mere recreational use, touching upon critical aspects of human health and cognitive function. This plant, characterized by its rich content of cannabinoids like delta-9-tetrahydrocannabinol (THC), has evolved over hundreds of years, adapting and being selectively bred by humans for its psychoactive and therapeutic properties. Its interaction with the brain’s endocannabinoid system, a natural network crucial for regulating mood, memory, and pain, reveals a complex narrative that includes not only the potential for therapeutic treatments but also the risks associated with addiction, memory impairments, mood alterations, and other adverse effects on cognition such as dissociation.