Document Type
Article
Publication Date
2-2015
Abstract
Background: Persons living with HIV (PLWH) are disproportionately burdened with methicillin-resistant Staphylococcus aureus (MRSA). Our objective was to evaluate prevalence and risks for MRSA colonization in PLWH. Methods: Adults were recruited from Johns Hopkins University AIDS Service in Baltimore, Maryland. A risk questionnaire and specimen collection from anatomic sites with culture susceptibility and genotyping were completed. Generalized estimating equation modeling identified MRSA colonization risk factors. Results: Of 500 participants,mostwere black (69%), on antiretroviral therapy (ART) (87%),with undetectable viral loads (73.4%). Median CD4 count was 487 cells/mm3 (interquartile range, 316-676.5 cells/mm3). MRSA prevalence was 15.4%, predominantly from the nares (59.7%). Forty percent were nares negative but were colonized elsewhere. Lower odds for colonizationwere associatedwith recent sexual activity (adjusted odds ratio [AOR]¼0.84, P$75,000; AOR ¼ 2.68, P < .001), recent hospitalization (AOR ¼ 1.54, P < .001), incarceration (AOR ¼ 1.55, P
Recommended Citation
Farley, J. E., Hayat, M. J., Sacamano, P. L., Ross, T., & Carroll, K. (2015). Prevalence and Risk Factors for MRSA in an HIV-positive Cohort. American Journal of Infection Control, 43(4), 329–335. http://doi.org/10.1016/j.ajic.2014.12.024
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This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Comments
Originally Published in:
Am J Infect Control, 43 (4), 329-35. doi: http://dx.doi.org/10.1016/j.ajic.2014.12.024