The purpose of this study is to examine the factors associated with alcohol related condom-less sex among youth living in the slums of Kampala, Uganda. Analyses are based on cross-sectional survey data, collected in 2014, of a convenience sample (n = 1134) of urban service-seeking youth participating in a Uganda Youth Development Link drop-in center. Logistic regression analyses were computed to determine the factors associated with intoxicated condom usage. The analytic sample consisted of only youth who responded to the dependent variable (n = 347), youth who reported not using a condom due while intoxicated and youth who reported using a condom while intoxicated. In the bivariate analysis, not using a condom while intoxicated was associated with being female (OR: 1.86; 95% CI: 1.21, 2.85), age of first drinking being between ages 13-16 (OR: 1.5; 95% CI: .79, 2.85), age of first time drunk being between ages 13-16 (OR: 2.88; 95% CI: 1.47, 5.67), binge drinking (OR: 3.64; 95% CI: 2.21, 5.98), rape (OR: 2.69; 95% CI: 1.64, 4.41), sex work (OR: 5.91; 95% CI: 3.09, 11.29), and being able to refuse sex when intoxicated (OR: 1.69; 95% CI: 1.10, 2.61). In the multivariable analysis, not using a condom while intoxicated was associated with being binge drinking (AOR: 2.97; 95% CI: 1.71, 5.17) and sex work (AOR: 3.48; 95% CI: 1.62, 7.49). The findings of this study emphasize many unmet needs of this vulnerable population. Strategies that specifically seek to address teenage alcohol prevention and delaying initial alcohol consumption may be particularly beneficial in this low-resource setting.