This research examines public health mapping over two time periods, 1944-1954 and 2000-2004 and explores how mapping disease shaped scientific knowledge about disease. During World War II, the Atlas of Diseases was produced by cartographers and geographers well versed in the subjectivity of maps. Today professionals in a variety of disciplines use digital mapping software to produce maps of disease. This research takes a look at how public health maps and mapping of disease have changed over time and discusses the political implications of public health mapping as an aspect of geographic governance.