Message passing interface (MPI) has been widely used for implementing parallel and distributed applications. The emergence of cloud computing offers a scalable, fault-tolerant, on-demand al-ternative to traditional on-premise clusters. In this thesis, we investigate the possibility of adopt-ing the cloud platform as an alternative to conventional MPI-based solutions. We show that cloud platform can exhibit competitive performance and benefit the users of this platform with its fault-tolerant architecture and on-demand access for a robust solution. Extensive research is done to identify the difficulties of designing and implementing an MPI-like framework for Azure cloud platform. We present the details of the key components required for implementing such a framework along with our experimental results for benchmarking multiple basic operations of MPI standard implemented in the cloud and its practical application in solving well-known large-scale algorithmic problems.