The physician’s crisis in Cameroon has reached an alarming stage and has the potential to worsen existing health problems including the attainment of millennium development goals. This report emphasized the challenges faced by Cameroonian physicians, and recommended alternative solutions to the current government health workers policies. The report was done through a review of articles and documents covering the topic. At the center of the physician’s crises in Cameroon is the discrepancy between financial, social and professional expectations and what the government offers. The analysis showed that, there is a general dissatisfaction, despite some corrective measures implemented by the government. This suggests that the government needs to aggressively adopt and implement aggressive retention policies, such as improving the remuneration and working conditions of health workers. Beside, there is also need for innovation by adopting and implementing solutions that have been successful in others countries. As in many other countries, establishing powerful unions and lobbying groups by Cameroon physicians may help in negotiating acceptable working conditions that could help in alleviating the challenges of Cameroonian physicians. Despite some limitations, this report can be useful for policy-makers in the formulation of effective human resources for health policies but also to draw attention to the need to publish more on human resources for health issues in Cameroon.