There are myriad definitions of the terms race, ethnicity and culture in social sciences literature. Often these terms are used interchangeably with no conceptual rationale. This study aims to contribute to our greater understanding of the similarities and differences between the conceptualization and use of race and culture as they are experienced by African American adolescents. Multiple regression analyses and factor analysis were conducted for 223 African American high school aged students who completed a survey about racial and ethnic identity and a variety of positive youth development outcomes. Results showed preliminary support for race and culture being distinguishable yet intricately related. Results are also presented that compares the relationship of either a racial or cultural orientation on various youth development outcomes.