The work presented in this thesis aims utilizes the versatility of cyanine dyes. Although large libraries have generated for these compounds, their remains an unmet need for alternative synthetic procedures that both optimizes and allows the dyes to be tailored for the desired use. The cyanine dye scaffold contains many points of modification but the central carbon remains a point that requires further research. In addition, among the heterocyclic compound that can be used in the synthesis of cyanine dyes, the quinoline heterocycle offer interesting optical variations to the dyes and can be utilized in the applications that do not require highly fluorescent compounds. The dyes presented showcase a superior synthetic procedure, and incorporate the quinoline heterocycle in novel compounds.