The trucking industry contributes $972 billion to U.S. gross domestic product and is responsible for moving in excess of 10 billion tons per year. The industry has faced significant challenges with driver shortages as well as high turnover. Additionally, over thirty-five thousand people lost their lives on U.S. highways in 2015, and 94% of these deaths were attributed to human error. Technologists are developing autonomous vehicle (AV) technology to address some of these challenges. AV technology has advanced significantly over the past decade and is now at a point where it is not a matter of if it is possible but when it will happen. This research will focus specifically on the carriers’ ability to implement autonomous commercial (i.e. trucks) vehicles (ACV), that could have the possibility of replacing truck drivers. Our investigation concerns the organizational readiness of trucking carriers, positing the following research question: What is the organizational readiness for the disruption caused by autonomous commercial vehicles (trucks)?