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On Coalescence Analysis Using Genealogy Rooted Trees

Yuan, Ao
Qin, Gengsheng
He, Wenqing
Li, Qizhai
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Abstract

DNA sequence data are now being used to study the ancestral history of human population. The existing methods for such coalescence inference use recursion formula to compute the data probabilities. These methods are useful in practical applications, but computationally complicated. Here we first investigate the asymptotic behavior of such inference; results indicate that, broadly, the estimated coalescent time will be consistent to a finite limit. Then we study a relatively simple computation method for this analysis and illustrate how to use it.

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Origingally Published in: Comput Math Methods Med, 2014 194202. DOI: 10.1155/2014/194202 Copyright © 2014 Ao Yuan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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2014-01-01
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Yuan, Ao, Qin, Gengsheng, He, Wenqing, Li, Qizhai, On Coalescence Analysis Using Genealogy Rooted Trees, Computational and Mathematical Methods in Medicine, 2014, 194202, 8 pages, 2014. https://doi.org/10.1155/2014/194202
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