This project examines drug addiction and personal responsibility from the perspective of three different types of theories of addiction: full responsibility, diminished responsibility, and no responsibility. The rational theory of addiction is the fully responsibility theory. The philosophical insights by R. Jay Wallace and George Graham are the diminished responsibility theories. Berridge and Robinson’s Incentive Salience theory of drug addiction is the no responsibility theory examined. My conclusion is that diminished responsibility frameworks are the most suitable in a therapeutic context because they are most sensitive to relevant normative aspects.