The Sustainable Development Goal (SDGs) number three aims to achieve good health and well-being. In order to achieve SDG3, WHO has identified many health targets including the achievement of Universal Healthcare Coverage (UHC). National Public Health Institutes (NPHIs) serve as the focal point for a country’s public health activities. Without an NPHI, public health activities can be fragmented with responsibility spread across multiple entities. This can lead to inefficiency, a lack of leadership and accountability, and ultimately, a reduced impact of programs. NPHI coordination of public health functions strengthens health systems and public health infrastructure overall. The goal of this capstone is to discuss the link between NPHIs, health system strengthening efforts, and UHC, and specifically, how having a strong NPHI contributes to UHC.