Antibiotic Resistance in Campylobacter is a growing global health concern, especially among vulnerable populations. Contamination and infection often start in food production, when meat is slaughtered and bacteria have time to grow, or in water contamination from wastewater runoff that is not adequately treated before consumption. When severe infection occurs, antibiotics are administered to assist with recovery. These antibiotics fall into five classes with the addition of multi-drug-resistant fluoroquinolones, macrolides, tetracyclines, aminoglycosides, and betalactams. Each antibiotic has a specific property to combat campylobacter. However, they also have specific resistant mechanisms, such as a genetic mutation, that allow resistance. This Systematic Review seeks to evaluate the status of antibiotic resistance.