Loading...
Thumbnail Image
Item

Direct Adjustment Method on Aalen's Additive Hazards Model for Competing Risks Data

Akcin, Haci Mustafa
Citations
Altmetric:
Abstract

Aalen’s additive hazards model has gained increasing attention in recently years because it model all covariate effects as time-varying. In this thesis, our goal is to explore the application of Aalen’s model in assessing treatment effect at a given time point with varying covariate effects. First, based on Aalen’s model, we utilize the direct adjustment method to obtain the adjusted survival of a treatment and comparing two direct adjusted survivals, with univariate survival data. Second, we focus on application of Aalen’s model in the setting of competing risks data, to assess treatment effect on a particular type of failure. The direct adjusted cumulative incidence curve is introduced. We further construct the confidence interval of the difference between two direct adjusted cumulative incidences, to compare two treatments on one risk.

Comments
Description
Date
2008-04-21
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Keywords
Survival function, Cumulative incidence function, Competing risks, Survival analysis, Aalen’s additive hazards model, Direct adjustment method
Citation
Akcin, Haci Mustafa. "Direct Adjustment Method on Aalen's Additive Hazards Model for Competing Risks Data." 2008. Thesis, Georgia State University. https://doi.org/10.57709/1059701
Embargo Lift Date
2012-01-26
Embedded videos