Date of Award

Summer 6-22-2011

Degree Type


Degree Name

Master of Science (MS)


Mathematics and Statistics

First Advisor

Dr. Jun Han

Second Advisor

Dr. Yuanhui Xiao

Third Advisor

Dr. Yichuan Zhao


This paper proposes a mixture of experts recurrent events model. This general model accommodates an unobservable frailty variable, intervention effect, influence of accumulating event occurrences, and covariate effects. A latent class variable is utilized to deal with a heterogeneous population and associated covariates. A homogeneous nonparametric baseline hazard and heterogeneous parametric covariate effects are assumed. Maximum likelihood principle is employed to obtain parameter estimates. Since the frailty variable and latent classes are unobserved, an estimation procedure is derived through the EM algorithm. A simulated data set is generated to illustrate the data structure of recurrent events for a heterogeneous population.


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Mathematics Commons