Date of Award

8-12-2016

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Mathematics and Statistics

First Advisor

Yi Jiang

Second Advisor

Gengsheng Qin

Third Advisor

Remus Osan

Abstract

Chronic inflammation increases the risk of developing cancer. We aim to investigate the molecular pathway of inflammation induced cancer by comparing gene expression in colorectal (CRC) tumors of patients with inflammatory bowel disease (IBD) to sporatic colorectal tumors. Since mRNA microarray data of IBD induced CRC is not readily available, we attempt to isolate IBD patients in a public database based on their gene expression signatures.

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