Geometric Analysis of Soft Thresholds in Action Potential Initiation and the Consequences for Understanding Phase Response Curves and Model Tuning
We perform visualization of the nullcline dynamics around threshold, and characterize important geometric properties via dominant scale analysis, which avoids the need to make asymptotic approximations. In particular, we analyze the transient dynamics during the passage through the ghost of a saddle-node bifurcation in the (V, m) phase-plane projection of a local 3D approximation to the 4D H-H equations (where sodium inactivation h is held constant).
Clewley and Chung: Geometric analysis of soft thresholds in action potential initiation and the consequences for understanding phase response curves and model tuning. BMC Neuroscience 2012 13(Suppl 1):P165. doi: 10.1186/1471-2202-13-S1-P165
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This poster presentation was originally published in BMC Neuroscience. It is posted here with the permission of the author.
Copyright © 2012 Clewley and Chung; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.