To determine effects of school breaks on influenza virus transmission in the Southern Hemisphere, we analyzed 2004–2010 influenza-like–illness surveillance data from Chile. Winter breaks were significantly associated with a two-thirds temporary incidence reduction among schoolchildren, which supports use of school closure to temporarily reduce illness, especially among schoolchildren, in the Southern Hemisphere.
G. Chowell, S. Towers, C. Viboud, R. Fuentes, V. Sotomayor. Age-specific rates of influenza-like illness and winter school breaks in Chile, 2004-2010. Emerging Infectious Diseases 20(7):1203-7 (2014).