Date of Award

8-3-2007

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Physics and Astronomy

First Advisor

Gennady Cymbalyuk - Chair

Second Advisor

Andrey Shilnikov

Third Advisor

Donald Edwards

Fourth Advisor

Vadym Apalkov

Fifth Advisor

Unil Perera

Abstract

The co-existence of bursting activity and silence is a common property of various neuronal models. We describe a novel mechanism explaining the co-existence of and the transition between these two regimes. It is based on the specific homoclinic and Andronov-Hopf bifurcations of the hyper- and depolarized steady states that determine the co-existence domain in the parameter space of the leech heart interneuron models: canonical and simplified. We found that a sub-critical Andronov-Hopf bifurcation of the hyperpolarized steady state gives rise to small amplitude sub-threshold oscillations terminating through the secondary homoclinic bifurcation. Near the corresponding boundary the system can exhibit long transition from bursting oscillations into silence, as well as the bi-stability where the observed regime is determined by the initial state of the neuron. The mechanism found is shown to be generic for the simplified 4D and the original 14D leech heart interneuron models.

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