Date of Award
8-3-2007
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Physics and Astronomy
First Advisor
Gennady Cymbalyuk - Chair
Second Advisor
Andrey Shilnikov
Third Advisor
Donald Edwards
Fourth Advisor
Vadym Apalkov
Fifth Advisor
Unil Perera
Abstract
The co-existence of bursting activity and silence is a common property of various neuronal models. We describe a novel mechanism explaining the co-existence of and the transition between these two regimes. It is based on the specific homoclinic and Andronov-Hopf bifurcations of the hyper- and depolarized steady states that determine the co-existence domain in the parameter space of the leech heart interneuron models: canonical and simplified. We found that a sub-critical Andronov-Hopf bifurcation of the hyperpolarized steady state gives rise to small amplitude sub-threshold oscillations terminating through the secondary homoclinic bifurcation. Near the corresponding boundary the system can exhibit long transition from bursting oscillations into silence, as well as the bi-stability where the observed regime is determined by the initial state of the neuron. The mechanism found is shown to be generic for the simplified 4D and the original 14D leech heart interneuron models.
DOI
https://doi.org/10.57709/1059799
Recommended Citation
Malashchenko, Tatiana Igorevna, "A Mechanism of Co-Existence of Bursting and Silent Regimes of Activities of a Neuron." Thesis, Georgia State University, 2007.
doi: https://doi.org/10.57709/1059799