Date of Award
1-12-2006
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Dr. Davon Kennedy - Chair
Second Advisor
Dr. Paul Franklin
Third Advisor
Giovanni Gadda
Fourth Advisor
Dr. Alfons Baumstark
Abstract
A series of penta-aryl/alkyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrazole 5a-c was synthesized by addition of methyllithium or phenylllithium followed by trapping the nitrogen anion intermediate with tosyl-fluoride to cyclic azines 2a,b. Addition of methyllithium or phenyllithium to 5a-c generated a series of hexa-aryl/alkylsubstituted-4,5-dihydro-3H-pyrazoles 6a-c. Neat thermolysis of hexa-aryl/alkylsubstituted-4,5-dihydro-3H-pyrazoles 6a-c at 200◦C produced hexa-aryl/alkylsubstituted cyclopropanes 7a-c in high yield.
DOI
https://doi.org/10.57709/1059223
Recommended Citation
Truong, Phong Minh, "Hexa-aryl/alkylsubstituted Cyclopropanes." Thesis, Georgia State University, 2006.
doi: https://doi.org/10.57709/1059223