Date of Award
4-30-2008
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Dr. Keith Pascoe - Chair
Second Advisor
Dr. Alfons Baumstark - Co-Chair
Third Advisor
Dr. Jerry Smith
Fourth Advisor
Dr. Davon Kennedy
Abstract
The purpose is to isolate a natural compound, which shows a high activity against Candida albicans, from plant, Vincetoxicum stocksii. Bio-Assay, Thin layer Chromatography, Column Chromatography, TLC bio Assay, and other extraction techniques are used in order to isolate the active compound. First, bio assay technique is carried out on the crude gum. Next, several flash chromatography columns are carried out in order to isolate the target compound, which has a Rf value of ~0.53 in 10:1 DCM/methanol solvent mixture. The TLC bioassay technique is also carried out in order to confirm the hypothesis that the target compound is indeed active.
DOI
https://doi.org/10.57709/1059230
Recommended Citation
Momin, Vasim Rasul, "The Analysis of Antimicrobial Testing Vincetoxicum stocksii and Isolation of a Highly Active Compound Against Candida albicans by Using Various Different Techniques.." Thesis, Georgia State University, 2008.
doi: https://doi.org/10.57709/1059230