Date of Award
8-12-2016
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
First Advisor
Maged M. Henary
Second Advisor
Alfons Baumstark
Third Advisor
Markus Germann
Abstract
This thesis begins with a brief review about the role and importance of the small molecules containing fluorine atoms in medicine and imaging. Then, the first part of the thesis will discuss the synthesis, purification and characterization of pentamethine cyanine dyes. The structure identification of the final dyes is done by using 1H NMR, 13C NMR, 19F NMR, and mass spectrometry. The studies performed after full characterization were the determination of optical and physicochemical properties. After these properties were performed, the fluorophores were evaluated to be good candidates for in vivo testing.
DOI
https://doi.org/10.57709/8867696
Recommended Citation
Dost, Tyler L., "Synthesis and Determination of Optical Properties of Selected Pentamethine Carbocyanine Dyes." Thesis, Georgia State University, 2016.
doi: https://doi.org/10.57709/8867696