Date of Award
7-31-2007
Degree Type
Closed Thesis
Degree Name
Master of Public Health (MPH)
Department
Public Health
First Advisor
Derek Shendell - Chair
Second Advisor
Jan Cragan
Third Advisor
Ike Okosun
Fourth Advisor
Adolfo Correa
Abstract
Caffeine, a mild central nervous system stimulant, is a natural component of common hot and cold beverages like coffee, tea, sodas and cocoa. Animal studies have demonstrated caffeine’s teratogenic effects when administered at high concentrations; however, epidemiologic studies have yielded inconsistent results in humans. Because caffeine containing beverages are commonly consumed by pregnant women, we examined the prevalence of use and explored possible associations of maternal caffeine consumption with cardiovascular malformations in 3,274 cases matched with 3,519 controls enrolled in the 1981-89 “Baltimore-Washington Infant Study,” a population-based case-control investigation. We explored several key aspects of the quality of and distribution of measurements of caffeine consumption among mothers in the study population. We concluded with recommendations for refining data collection to reduce potential bias associated with assessing both caffeine content and changes in caffeine consumption during pregnancy in order to inform future research studies and birth defects/adverse birth outcomes surveillance programs.
DOI
https://doi.org/10.57709/1062242
Recommended Citation
Daniel, Johnni Hutcherson, "Analyzing Limitations in Exposure Estimates Based on Self-Reported Dietary Intake of Caffeinated Beverages in the Baltimore-Washington Infant Study, 1981-1989." Thesis, Georgia State University, 2007.
doi: https://doi.org/10.57709/1062242