Theses from 2024
Synthesis of Novel Tryptophan Drug Candidates for Thera(g)nositcs for the Human Calcium Receptor, Matthew Goodman
Exploring Calcium Sensing Mechanisms via the Calcium Sensing Receptor, Oluwadamilola Rosemary Ilupeju
Exploration of the Molecular Mechanisms of E3 Ligases RNF216, Rsp5, Parkin and their Novel Substrates Elucidated by the Orthogonal Ubiquitin Transfer Cascade, Savannah E. Jacobs
Theses from 2023
Insights into the Local Structural Impact of Ribonucleotide Inclusion in Duplexed DNA, Steven T. Brenden
Catalytic Production of Carbon Monoxide from Phenyl Pyruvic Acid: Possible Therapeutic and Diagnostic Applications, Rujuta Ghorpade
Optimization of the Purification and Formation of hProCA32 for Human Clinical Application, Hyein Kang
The Production of DNA Damaging Reactive Oxygen Species (ROS) by Some Natural Products: A Comparative Analysis, Erhunmwense Obayuwana
Synthesis and Optical Properties of Red Shifted Squaraine Dyes Containing Perimidine Moiety as Potential Optoacoustic Imaging Agents, Shahir Sarasiya
Theses from 2022
Negative Differential Resistance in The Rectified Ion Transport Hysteresis in Single Conical Nanopipettes, Yusuff Mobolaji Balogun
Bioreversible Derivatization of Drug Molecules with a Pyridine Ring for Improved Water Solubility: Model Studies, Shubham Bansal
Investigation into Novel Mitochondrial Targeting Cyanine Dyes as Potential Photosensitizing Agents for Photodynamic Therapy, David Brewer
Ultrabright Fluorine Containing Squaraine Fluorophores Used for Biological Imaging, Stefanie Casa
Synthesis and Characterization of Carbon Monoxide Prodrugs, David B. Cohen
Synthesis and Optical Properties of Near Infrared Donor-ᴫ-Acceptor Fluorophores for Bioimaging Applications, Ranju Ghimire
Calcium Sensing Via The Calcium-Sensing Receptor and Designed Calcium Sensors, Cheyenne T. McBean
Formulation and Production of Collagen Targeting Protein MRI Contrast Agent for Early Detection of Liver Cancer and fibrosis, Brenda-Ruth Mimba
Mechanistic Investigation of a Non-Catalytic Gating Residue in NADH:Quinone Oxidoreductase from Pseudomonas aeruginosa PA01, Bilkis Mehrin Moni
Dye-Sensitized DNA Photocleavage Facilitated by Donor-Acceptor Fluorophores in the NIR Wavelength Range, Carine Seudieu
Synthesis, and Characterization of Hemicyanine Dyes as Potential Contrast Agents for Photoacoustic Imaging, Tuyen Tran
Enzyme Kinetics and Structural Studies of Drug Resistant HIV Protease, Sarah R. Verhoff
Theses from 2021
Genomic Epidemiology Analysis of SARS-CoV-2 Transmission Dynamics in Belarus, Ayotomiwa Ezekiel Adeniyi
Mechanistic Characterization of Active Site Residues in Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1, Christopher Aguillon
Unprecedented DNA Photocleavage Mediated by Quinolinium Pentamethine Carbocyanine Dyes in the NIR Wavelength Range, Effibe O. Ahoulou
A Comparative Study of Oxycyclobutenolate vs Dicyanomethylene Squaraine Dyes: Synthesis, Photophysical Properties and Biological Imaging Application, Babatunde N. Animasaun
Functional Importance of Non-Catalytic Residues in the Active Site of NADH:Quinone Oxidoreductase From Pseudomonas aeruginosa PA01, Benjamin Dratch and Gioavanni Gadda
Synthesis and Optical Properties of Red Shifted Donor Acceptor Fluorophores as Potential Agents for Biomedical Applications, Guliz Ersoy Ozmen
Calculated Vibrational Properties of Asymmetrically Hydrogen Bonded Benzoquinones and Naphthoquinones, Mohammadnabi Ilanikashkouli
Enhancement of Anti-tumor Efficacy of an Armed Oncolytic Virus: VSV-SKPC, Breona Luker
An Experimental Benchmark Set for Oscillator Strength Calculations of Small to Medium-sized Organic Molecules, Astrid Tarleton
Theses from 2020
Characterization of Heme Binding to PEFR, A Marr Transcriptional Regulator, Rosemary Andrews
An Innovative Way To Synthesize 2'-SeMeANA-U AND 2'-SeMeANA-C, Mohammad Sazid Hassan
Synthesis, Characterization, Optical Properties and DNA Cleavage Study of Symmetrical Pentamethine Cyanine Dyes Containing Quinoline Moieties, Kristina Ilina
The Synthesis and Optical Properties of the Squaraine Scaffold and Ph Responsive Cyanine Dyes Containing Pyridine at the Meso-Carbon, Wheeler R. Lovett
Simulation of Photoelectron Spectra of Small Organic Molecules, MD Mahbub
Theses from 2019
Biophysical Properties of DNA Minor Groove Binding by Heterocyclic Cations of Varying Structures, Noa Erlitzki
Photoelectron Spectra and Formation Mechanisms of Interstellar C3H2O Isomers from Quantum Mechanical Calculations, Rebecca Johnson
Exploring the Dynamics of Glycolytic Regulation Through Two Enzymes: Human Enolase and Liver Pyruvate Kinase, Abdullah Shouaib
Synthesis and Properties of Lipoic Acid Stabilized Gold Nanoclusters, Minh Tri Tran
Kinetic Viscosity Effects Reveal a Protein Isomerization in the Reductive Half-Reaction of Nitronate Monooxygenase, Maria Vodovoz
Computational Study on Protein Arginine methyl-transferases (PRMTs), Zhenyu Wang
Theses from 2018
Atomic Resolution X-Ray Crystal Structure of HIV-1 Protease in Complex with Atazanavir, Andrew N. Baumert
Elucidating Ubiquitin Chain Formation Catalyzed by E2 Enzymes through use of a Di-Ubiquitin Probe, Tomaya Carpenter
Investigation of Low-Temperature Effects on DNA Photocleavage Using a Novel Thioether Substituted Cyanine Dye, Andrew Clay
Improvement Of Vesicular Stomatitis Virus In Order To Enhance Its Oncolytic Effects, Zahra Enadi
Characterizing the Heme Uptake Proteins HtaB and ChtB in Corynebacterium diphtheriae, Brandon L. Ferrell
Understanding Integrase-DNA Interactions in Retroviruses Through 3'-processing, Zachary E. Ferris and Markus W. Germann
Synthesis and Photophysical Properties of Phenoxazine Analogs Designed as Potential Antimalarials, Carl Mufungwa Kananda
The Utilization of Alternative Synthetic Methods for Further Optimization of Cyanine Dyes and their Potential Use in Imaging and Photodynamic Therapy, Fahad Marmarchi
The Energetics and Reversibility of Oxyanions Adsorption/Desorption on Pure and Aluminium-Substituted Ferrihydrite, Alireza Namayandeh
Determination of Mouth-level Exposure to Catechol in Mainstream Cigarette Smoke, Phuong K. Ngac
Determining xE2-xE3 Pair of RNF38 by Phage Display for Orthogonal Ubiquitin Transfer, Nicolas Rios
Synthesis and Analysis of Pyridine Derivatives as Small Molecule Antagonists of CXCR4, Saniya Virani
A Novel Method for Synthesis of 2'-SeMeANA-dT, Lingrui Zheng
Theses from 2017
Pirin Allosterically Modulates The Dynamics And Interactions Of The Kappa B DNA In The NF-Kappa B Supramolecular Complex, Charles Adeniran
Organic Carbon Monoxide Prodrugs, Robert Aghoghovbia
Cation Adsorption and Exchange at the Mineral-Water Interface: The Role of Hydration and Hydrolysis, Nicholas Allen
Insulin Nucleation Using Voltage Clamping and Current Clamping Techniques, Michael J. Bowen
Synthesis Of Novel Organic Carbon Monoxide Prodrugs With Tunable Release For Biological Applications, Vayou Chittavong
Analysis Of DNA Interactions and Photocleavage by Phenyl Meso Substituted Cyanine Dyes In The Near-Infrared Range, Christina Fischer
Synthesis & Evaluation Of Thiophene Derivatives As CXCR4 Antagonists, Francisco Javier Garcia Jr.
Investigation and Characterization of Novel Pentamethine Cyanine Dyes for Use as Photosensitizers in Photodynamic Therapy, Kaitlyn Kiernan
Atomistic Insights into Binding Pocket Dynamics and Regulation in the Interleukin-2 T-Cell Kinase SH2 Domain, Mohamed Momin
DNA Encoded Libraries (DEGL) of Glycan Antigens to Detect Antibodies: An Approach Towards Next Generation Functional Glycomics, Aishwarya Parameswaran
Biophysical Heme Binding Studies of Corynebacterium diphtheriae and Streptococcus pyogenes, Stephanie Thompson
Determination of Dynamical Conservation in Human Cyclophilin Isoforms, Phuoc Jake D. Vu
Design and Synthesis of Inhibitors of Hypoxia Inducible Factor-1-mediated Functions, Lingyun Yang
Chemoenzymatic Synthesis of UDP-GlcNAc and UDP-GalNAc Derivatives for Chemoenzymatic Labeling, Yuan Zheng
Theses from 2016
Synthesis of 2SeU-RNAs and RNA Squares, Xinghua Chen
Synthesis and Determination of Optical Properties of Selected Pentamethine Carbocyanine Dyes, Tyler L. Dost
DNA Photo-Cleavage and Interactions by Quinoline Cyanine Dyes; Towards Improving Photodynamic Cancer Therapy, Tayebeh Fatemipouya
Optical Property Enhancement And Characterization Of Fluorescent Protein Based Intracellular Calcium Probes, Demesheka Goolsby
Spectroscopic and Thermodynamic Characterization of Human 3-Hydroxyanthranilate-3,4-Dioxygenase, Calmour Henry
Synthetic Development of Cyanine Dyes and Investigation of Their Interaction with Duplex DNA, Cory Holder
Study Of The DNA Packaging Protein From A Phage That Replicates Under Extreme Conditions, Philip Lessans
Modifications To The Benzophenoxazine Architecture: Synthesis And Characterization, Vincent Martinez
An Investigation of the DNA Interactions of Polyamine Anthracene Conjugates under High Ionic Conditions, Khoa Nguyen
Establishing the Relationship Between Function and Dynamics Within the Gated Mechanism of D-arginine Dehydrogenase, Michael Souffrant
Investigation Of A Novel Mammalian Thiol Dioxygenase Structure: Human Cysteamine Dioxygenase, Tseng Xiong and Tseng Xiong
Theses from 2015
Cyanine Dyes Targeting G-quadruplex DNA: Significance in Sequence and Conformation Selectivity, Hang T. Huynh
Spectroscopic Studies of Cyanine Dyes and Serum Albumins for Bioanalytical Applications, Erica Lewis
Synthesis of Sulfated Polysaccharides for Colitis Mice Model, Qiang Ma
Observation Of Spectral Changes To Trp-214 Residue In Human Serum Albumin Upon Binding With Mangiferin And Near Infrared Dyes, Jennifer Novak
Mechanistic Investigation of the Flavin-Neighboring Residues S45, A46 and I335 in Pseudomonas aeruginosa D-arginine Dehydrogenase, Daniel Ouedraogo and Gioavanni Gadda
Development of New Series of Protein Based MRI Contrast Agents: ProCA1 Variants and Humanized ProCA32, Anvi N. Patel
Protein Modification of Designed MRI Contrast Agents, Corrie N. Purser